RO 8994
RO8994
CAS: 1309684-94-3
Molecular Formula: C31H31Cl2FN4O4
RO 8994 - Names and Identifiers
| Name | RO8994 |
| Synonyms | RO8994 CS-2264 RO 8994 RO-8994 (2'S,3R,4'S,5'R)-N-[4-(Aminocarbonyl)-2-methoxyphenyl]-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-1,2-dihydro-2-oxo-spiro[3H-indole-3,3'-pyrrolidine]-5'-carboxamide Spiro[3H-indole-3,3'-pyrrolidine]-5'-carboxamide, N-[4-(aminocarbonyl)-2-methoxyphenyl]-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-1,2-dihydro-2-oxo-, (2'S,3R,4'S,5'R)- |
| CAS | 1309684-94-3 |
RO 8994 - Physico-chemical Properties
| Molecular Formula | C31H31Cl2FN4O4 |
| Molar Mass | 613.51 |
| Density | 1.41±0.1 g/cm3(Predicted) |
| Boling Point | 753.5±60.0 °C(Predicted) |
| Solubility | DMSO: ≥ 45 mg/mL |
| pKa | 12.00±0.70(Predicted) |
| Storage Condition | -20℃ |
RO 8994 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.63 ml | 8.15 ml | 16.3 ml |
| 5 mM | 0.326 ml | 1.63 ml | 3.26 ml |
| 10 mM | 0.163 ml | 0.815 ml | 1.63 ml |
| 5 mM | 0.033 ml | 0.163 ml | 0.326 ml |
Last Update：2024-01-02 23:10:35
RO 8994 - Reference Information
| biological activity | RO8994 is a highly effective selective MDM2 inhibitor, IC50 is nM (HTRF binding assay) and 20 nM (MTT proliferation assay). |
Last Update：2024-04-09 21:04:16
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Product Name: RO8994 Visit Supplier Webpage Request for quotation
CAS: 1309684-94-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 1309684-94-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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